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Saturday, 19 May 2012 03:30
Swedish companies can reduce side effects Print E-mail

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There is no flu vaccine; you get sick of, but the ingredients. Now, a Swedish company has developed an additive that will reduce side effects.

Fever, nausea, stomach pain and body, it is not unusual to be short-term sick after having been vaccinated against swine flu. But it is usually not the vaccine (antigen) that makes us sick, but the excipient that are mixed in solution. They are necessary for our immune system to catch sight of the antigen and to boost the production of antibodies that protect us against the flu.

Uppsala Isconova the Company has developed a new excipient, or adjuvant, as our bodies apparently do not react as strongly against.

- Studies that we have done in Norway shows that the body tolerates the subject very well, "said Lena Soderstrom, managing director at Isconova.

It turned out including the vaccinated rarely got the usual side effects pain and fever.

- Our adjuvant also seems to give a better response from the immune system of the elderly and children than older types of excipients. In addition, activates the T cells, allowing the efficacy of the vaccine remain longer in the body.

There are results that point to the possibility of more effective vaccines for the elderly and children, who do not have as good immune system as other age groups. But the benefits do not stop at that. The new adjuvant also increases the possibility of creating vaccines for diseases that have not gone to get the vaccine. These include herpes.

Isconova recently signed a contract with a major U.S. vaccine company. What is the current situation is not public, but the company is working in areas other than influenza.

As can be vaccinated with Isconovas product entering the market?

"It will probably take several years. In the case of vaccines for use in humans are very high requirements. Therefore, we are planning for more studies, "said Lena Soderstrom.
 
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